If you have a performance issue on Mac OS X when launching and closing SPSS Statistics 21 or 22, you need to delete a preference file.
Delete the following file: com.ibm.spss.plist on your computer to dramatically reduce the opening and closing of the SPSS software.
This file is in /Library and ~/Library. Restart after deleting (this might not be necessary).
Note 1: this means opening the Library folder in your home folder, and/or the Library folder you see when opening the system disk (usually called "Macintosh HD").
Note 2: If you cannot see the home library folder, go to the Finder (desktop) app, and choose "Library" from the "Go" menu.